BIOL 4415 - Introduction to Bioinformatics

3 Class Hours 3 Laboratory Hours 4 Credit Hours
Prerequisite: A grade of “B” or better in BIOL 3300; a grade of “C” or better in MATH 1190; pre- or co-registration in BIOL 3410; or permission of the instructor.
Students use the fundamental concepts of biological sequence analysis, including information flow in biological systems and use of sequence and structure databases in research and drug discovery, which are the underpinnings of the genomic revolution. Students will: assemble sequencing reads into contigs; find and annotate protein coding genes; search biological databases; perform sequence alignments; analyse the phylogenetic relationships between sequences; assess the statistical significance of assembly, search and alignment results; and predict protein structure.